

Chemistry 481
Biochemistry
Spring 2005
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Instructors:
Jane Finan
email: jfinan@lcsc.edu
A. Course objectives:
Chemistry 481, a one-semester survey of biochemistry, is designed to introduce students to the chemistry of biological molecules and metabolic pathways. Structure and metabolic pathways of proteins, lipids, carbohydrates, and nucleic acids will be emphasized, as well as integration of these metabolic pathways in biological systems.
B. Course prerequisites:
All students enrolled in this course must have successfully completed Chemistry 372 with a grade of C or better. If you have not met this prerequisite you must meet with instructor to gain permission to enroll in the class.
C. Required textbook:
Lehninger’s Principles of Biochemistry.
D. Methods of Instruction and Student Responsibilities:
This course will be primarily taught in a lecture format with time provided for student discussion and student questions. Students are responsible for all lecture materials and assigned review questions.
In the case of an absence, it is the student’s responsibility to obtain the information, which they missed (this includes any announcements regarding exams). Students who miss an exam or quiz must contact the instructor within 24 hours of the missed exam or quiz. Students who fail to do so will NOT be allowed to make-up the missed exam. Students may only make up an exam or quiz if there was a valid and extraordinary reason for missing the exam such as illness. Exams or quiz may not be made up if a vacation or personal trip is scheduled on an exam date. Make-up exams and quizzes will cover the same material as the original exam but will not necessarily be in the same format. Any student who is absent for the final exam (for a valid reason) and has a passing grade at the time of the final exam will earn an incomplete for the semester and will take the final exam during the next semester. Drop slips will not be signed after March 25, 2005. There will be no exceptions to this final withdrawal date.
If you need course adaptations or accommodations because of a disability, if you have emergency medical information to share with me, or if you need special arrangements in the building must be evacuated, please make an appointment to talk with me.
E. Evaluation:
Final grades will be based on scores earned on exams and quizzes given throughout the semester. There will be 3 exams each worth 100 points for a total of 300 points. There will be 6 quizzes 15 points for a total of 90 points. Final grades will be calculated by adding total points scored and dividing the total by 3.9.
Final grades will be based on the following:
93-100% = A 90-92% = A- 87-89% = B+ 83-86% = B 80-82% =B- 77-79% = C+ 73-76% = C 70-72% = C- 67-69% = D 60-66% =D less than 60% = F
There is no extra-credit work or grading curve in this course.
F. Course content:
DATE |
TOPIC |
REFERENCE |
January 10 |
Introduction/Amino Acids
|
Chp. 3 |
|
January 12 |
Amino Acid Properties
|
Chp. 3 |
|
January 17 |
No class
|
|
|
January 19 |
Peptides & proteins
|
Chp. 3/4 |
|
January 24** |
Quiz 1/proteins
|
Chp. 4 |
|
January 26 |
Proteins
|
Chp. 4 |
|
January 31 |
Enzymes
|
Chp. 6 |
|
February 2 |
Enzymes
|
Chp. 6 |
|
February 7** |
Quiz2/ carbohydrate structure
|
Chp. 7 |
|
February 9 |
Carbohydrate structure & Glycogen synthesis |
Chp. 7 |
|
February 14 |
Exam I
|
|
|
February 16** |
Glycogen/Glycolysis
|
Chp. 14 |
|
February 21 |
No Class
|
|
|
February 23 |
Glycolysis/Gluconeogenesis
|
Chp. 14 |
|
February 28 |
Lipid Structure
|
Chp. 10 |
|
March 2** |
Quiz 3/Lipid Structure
|
Chp. 10 |
|
March 7 |
Lipid Metabolism
|
Chp. 17 |
|
March 9 |
Lipid Metabolism
|
Chp. 17 |
|
March 21 |
Aerobic Metabolism: TCA Cycle
|
Chp. 16 |
|
March 23** |
Quiz 4/ Aerobic Metabolism: Oxidative Phosphorylation |
Chp. 19 |
|
March 28 |
Aerobic Metabolism
|
Chp. 19 |
|
March 30** |
EXAM II
|
|
|
April 4 |
Nitrogen Metabolism: Synthesis
|
Chp. 18 |
|
April 6 |
Nitrogen Metabolism: Synthesis and Degradation |
Chp. 18/22 |
|
April 11 |
Nitrogen Metabolism: Synthesis
|
Chp. 18/22 |
|
April 13** |
Quiz 5/ Integration of Metabolism
|
Chp. 23 |
|
April 18 |
Integration of Metabolism |
Chp. 23 |
|
April 20 |
Nucleic Acids
|
Chp. 8 |
|
April 25 |
DNA Replication
|
Chp. 24 |
|
April 27** |
Quiz 6/DNA Replication
|
Chp. 24 |
|
May 02 |
TBA
|
|
May 04 |
TBA
|
|
May 09 |
Exam III |
|
If class is canceled on the day of an exam or quiz, the exam or quiz will be given during the next scheduled meeting of the class.
G. Instructor Availability
My office is room 221 in Merriwether Lewis Hall. I will be in my office from 10:30 am until 11:45 am Mondays and Wednesdays. Other times are available by appointment.